I recently returned from Africa where I used the 650gr Dr. Ashby Big Game system. It could not have worked better. I am a true believer in GrizzlyStiks.
If you look at the kudu picture, look below its right ear. That is the broadhead about to poke out on the opposite side. I took an extreme quartering away shot. The arrow entered right in front of the kudu's left hip. It went through and broke the leg on the opposite side. It went about 60yds and there was good blood. Everything else I shot was a full pass through except a warthog that I shot through both shoulders.